Police named the suspect as 25-year-old Jonathan Andrew Poff.
Officers used a 40-millimeter bullet-shaped device that makes a very loud sound to bring Poff out.
Police have arrested the suspect in the standoff on Salem Turnpike.
Roanoke Police received a call at 6:43 p.m. for a domestic disorder and a man with access to weapons.
At the time of the call, police say a female victim was inside, but she, reportedly a family member, has since come out safely. Police did not describe the extent of the victim's injuries; however, she did refuse to go to the hospital.
Charges of domestic assault and battery and violating a protective order are pending.
The Roanoke Police Department's tactical response team is on the scene. Police negotiators are trying to talk with the man. Officers have not released the suspect's name yet.
Roanoke City Police have blocked off Salem Turnpike between 30th and 31st Streets in Northwest due to a standoff.
Officers say a man has barricaded himself, and police believe he has access to weapons.
Extra officers have been called in to make sure the situation does not get out of control.
The area is about two blocks west of the Melrose Library branch.